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CD63

and the most popular subtypes like CD63+

CD63 Gene ID 967
CD63 Official Full Name CD63 molecule
CD63 Alias LIMP, LAMP-3, MLA1
CD63 Cellular Expression T; B; NK; Endothelial; Granulocyte; Macrophage; monocytes; Platelet
CD63 Ligand/Receptor/Association VLA-3, VLA-4, CD9, CD81
CD63 Function Cell growth and motility regulation; complexes with integrins
CD63 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

 

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