×

Registrierung

Profile Informationen

Login Daten

oder Einloggen

Vorname ist erforderlich!
Nachname ist erforderlich!
Vorname ist ungültig!
Nachname ist ungültig!
Dies ist keine E-Mail-Adresse!
E-Mail-Adresse ist erforderlich!
Dies E-Mail-Adresse ist bereit registriert!
Passwort ist erforderlich!
Geben Sie ein gültiges Passwort ein!
Bitte geben Sie 6 oder mehr Zeichen ein!
Bitte geben Sie 16 oder weniger Zeichen ein!
Passwörter sind nicht dasselbe!
Geschäftsbedingungen sind erforderlich!
E-Mail oder Passwort ist falsch!

CD218

and the most common subtypes like CD218a, CD218b and CD218+

CD218a - Cluster of differentiation 218a

CD218a Gene ID 8809
CD218a Official Full Name interleukin 18 receptor 1
CD218a Alias IL-18Rα, IL-1Rrp, IL18R1
CD218a Cellular Expression T; B; NK; Dendritic; Endothelial; Granulocyte; Macrophage; monocytes
CD218a Ligand/Receptor/Association IL-18
CD218a Function Forms part of the receptor complex for IL18
CD218a Summary The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

 

CD218b - Cluster of differentiation 218b

CD218b Gene ID 8807
CD218b Official Full Name interleukin 18 receptor accessory protein
CD218b Alias IL-18Rβ, IL18RAP
CD218b Cellular Expression T; B; NK; Dendritic; Endothelial; Macrophage; monocytes
CD218b Ligand/Receptor/Association  
CD218b Function Forms part of the receptor complex for IL18
CD218b Summary The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

 

All relevant products for CD218a, CD218b and CD218+

Set Descending Direction

2 Artikel

Set Descending Direction

2 Artikel