|CD18 Gene ID||3689|
|CD18 Official Full Name||integrin subunit beta 2|
|CD18 Alias||Integrin beta 2, ITGB2, MFI7|
|CD18 Cellular Expression||T; B; NK; Dendritic; Granulocyte; Macrophage; Platelet|
|CD18 Ligand/Receptor/Association||ICAMs, ECM|
|CD18 Function||Adhesion, cell signaling|
|CD18 Summary||This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]|
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