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CD202

and the most popular subtypes like CD202+

CD202b Gene ID 7010
CD202b Official Full Name TEK receptor tyrosine kinase
CD202b Alias Tie2, Tek
CD202b Cellular Expression Endothelial; Stem cell
CD202b Ligand/Receptor/Association angiopoietin
CD202b Function Signaling, migration and adhesion
CD202b Summary CD202b / cluster of differentiation 202b also known as Angiopoietin-1 receptor, is a protein that in humans is encoded by the TEK gene. CD202b possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in CD202b are associated with inherited venous malformations; the CD202b signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. CD202b is closely related to the TIE receptor tyrosine kinase.

 

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