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CD79a Gene ID | 12518 |
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CD79a Official Full Name | CD79A antigen (immunoglobulin-associated alpha) |
CD79a Alias | MB1, IGA, Ig-alpha |
CD79a Cellular Expression | B |
CD79a Ligand/Receptor/Association | |
CD79a Function | Subunit of B-cell antigen receptor.Signal transduction |
CD79a Summary | Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene.[1]The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR).[2] This occurs in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface.[3]It is associated with agammaglobulinemia-3.[4] |
CD79b Gene ID | 974 |
---|---|
CD79b Official Full Name | CD79b molecule |
CD79b Alias | B29, IGB, Ig-beta |
CD79b Cellular Expression | B |
CD79b Ligand/Receptor/Association | |
CD79b Function | Subunit of B-cell antigen receptor.Signal transduction |
CD79b Summary | The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |