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CD21 Gene ID | 12902 |
---|---|
CD21 Official Full Name | complement receptor 2 |
CD21 Alias | C3DR, CR2, EBV-R |
CD21 Cellular Expression | T; B; Dendritic; Epithelial; Stem cell |
CD21 Ligand/Receptor/Association | C3d, EBV, CD23 |
CD21 Function | Signal transduction. Regulator of complement activation |
CD21 Summary | Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene.CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d.[1] B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation [2] |