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CD200 Gene ID | 4345 |
---|---|
CD200 Official Full Name | CD200 molecule |
CD200 Alias | OX-2, OX2 |
CD200 Cellular Expression | T; B; Dendritic; Endothelial; Stem cell |
CD200 Ligand/Receptor/Association | OX2R |
CD200 Function | Down-regulatory signal for myeloid cell function, costimulates T-cell proliferation |
CD200 Summary | OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200)[1] is a human protein encoded by the CD200 gene.[2]The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.[2] |