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CD51
and the most popular subtypes like CD51+
| CD51 Gene ID | 3685 |
|---|---|
| CD51 Official Full Name | integrin subunit alpha V |
| CD51 Alias | Vitronectin receptor, ITGAV, MSK8 |
| CD51 Cellular Expression | T; Endothelial; Platelet |
| CD51 Ligand/Receptor/Association | fibrinogen, thrombospondin, vWF, CD242 |
| CD51 Function | Adhesion and signal transduction |
| CD51 Summary | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015] |
