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CD155
and the most popular subtypes like CD155+
| CD155 Gene ID | 5817 |
|---|---|
| CD155 Official Full Name | poliovirus receptor |
| CD155 Alias | PVR, NECL-5 |
| CD155 Cellular Expression | Macrophage; monocytes |
| CD155 Ligand/Receptor/Association | poliovirus, vitronectin, CD226, CD96, ��V��3, CD111, CD112 |
| CD155 Function | Mediates NK cell adhesion and triggers their effector functions. |
| CD155 Summary | The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
