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CD99 Gene ID | 4267 |
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CD99 Official Full Name | CD99 molecule |
CD99 Alias | MIC2, E2 |
CD99 Cellular Expression | T; B; NK; Endothelial; Epithelial; Erythrocyte; Granulocyte; Macrophage; monocytes; Platelet; Stem cell |
CD99 Ligand/Receptor/Association | cyclophilin A |
CD99 Function | Leukocyte migration, T-cell activation and cell adhesion |
CD99 Summary | The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016] |