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CD95 Gene ID | 14102 |
---|---|
CD95 Official Full Name | Fas (TNF receptor superfamily member 6) |
CD95 Alias | Apo-1, FASLG, APTL, TNFRSF6 |
CD95 Cellular Expression | T; B; NK; Granulocyte; Macrophage; monocytes |
CD95 Ligand/Receptor/Association | Fas ligand (CD95L, CD178) |
CD95 Function | Induces apoptosis |
CD95 Summary | The FAS receptor (FasR), also known as apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6) is a protein that in humans is encoded by the TNFRSF6 gene.[1][2]The Fas receptor is a death receptor on the surface of cells that leads to programmed cell death (apoptosis). It is one of two apoptosis pathways, the other being the mitochondrial pathway.[3] FasR is located on chromosome 10 in humans and 19 in mice. Similar sequences related by evolution (orthologs)[4] are found in most mammals. |