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CD89 Gene ID | 2204 |
---|---|
CD89 Official Full Name | Fc fragment of IgA receptor |
CD89 Alias | FcαR, FCAR |
CD89 Cellular Expression | B; Granulocyte; Macrophage; monocytes |
CD89 Ligand/Receptor/Association | IgA1, IgA2 |
CD89 Function | IgA Fc receptor |
CD89 Summary | This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |