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CD334
and the most popular subtypes like CD334+
CD334 Gene ID
2264
CD334 Official Full Name
fibroblast growth factor receptor 4
CD334 Alias
FGFR4, JTK2, TKF
CD334 Cellular Expression
Epithelial; Macrophage
CD334 Ligand/Receptor/Association
aFGF, FGF19
CD334 Function
Cell-surface receptor for fibroblast growth factors
CD334 Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Sensitivity: The minimum detectable dose of Human PDGFRA / CD140a was determined to be approximately 31.25 pg/ml. This is defined as at least three times standard deviations above the mean optical density of 10 replicates of the zero standard. Detection: 31.25 pg/ml
Sensitivity: The minimum detectable dose of Rat IL-1R2 / CD121b was determined to be approximately 12.5 pg/ml. This is defined as at least three times standard deviations above the mean optical density of 10 replicates of the zero standard. Detection: 12.5 pg/ml