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CD127 Gene ID | 3575 |
---|---|
CD127 Official Full Name | interleukin 7 receptor |
CD127 Alias | IL-7R, IL7R |
CD127 Cellular Expression | T; B; Macrophage; Stem cell |
CD127 Ligand/Receptor/Association | IL-7 |
CD127 Function | Receptor for IL7 |
CD127 Summary | The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015] |