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CD107a Gene ID | 16783 |
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CD107a Official Full Name | lysosomal-associated membrane protein 1 |
CD107a Alias | LAMP-1 |
CD107a Cellular Expression | T; Endothelial; Erythrocyte; Granulocyte; Macrophage; Platelet |
CD107a Ligand/Receptor/Association | |
CD107a Function | Cell adhesion |
CD107a Summary | Lysosomal-associated membrane protein 1 is a glyoprotein from a family of Lysosome-associated membrane glycoproteins.[1] The LAMP-1 glycoprotein is a type I transmembrane protein[2] which is expressed at high or medium levels in at least 76 different normal tissue cell types.[3] It resides primarily across lysosomal membranes,[4] and functions to provide selectins with carbohydrate ligands.[1] CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells.[5] and may also play a role in tumor cell differentiation and metastasis. |
CD107b Gene ID | 3920 |
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CD107b Official Full Name | lysosomal associated membrane protein 2 |
CD107b Alias | LAMP-2 |
CD107b Cellular Expression | T; Endothelial; Erythrocyte; Granulocyte; Macrophage; Platelet |
CD107b Ligand/Receptor/Association | |
CD107b Function | May be involved in leukocyte adhesion.Implicated in tumor cell metastasis |
CD107b Summary | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008] |