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CD18 Gene ID | 3689 |
---|---|
CD18 Official Full Name | integrin subunit beta 2 |
CD18 Alias | Integrin beta 2, ITGB2, MFI7 |
CD18 Cellular Expression | T; B; NK; Dendritic; Granulocyte; Macrophage; Platelet |
CD18 Ligand/Receptor/Association | ICAMs, ECM |
CD18 Function | Adhesion, cell signaling |
CD18 Summary | This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
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