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CD134
and the most popular subtypes like CD134+
| CD134 Gene ID | 22163 |
|---|---|
| CD134 Official Full Name | tumor necrosis factor receptor superfamily, member 4 |
| CD134 Alias | OX-40, TNFRSF4 |
| CD134 Cellular Expression | T |
| CD134 Ligand/Receptor/Association | CD134 ligand |
| CD134 Function | T-cell activation, proliferation and differentiation, apoptosis and cell adhesion |
| CD134 Summary | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting na?ve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels. |
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