Active Human Plasminogen Activator Inhibitor 1 (PAI1) ELISA Kit

Brand

Cell Sciences

Description

Plasminogen Activator Inhibitor 1 (PAI1) is the principal inhibitor of Tissue Plasminogen Activator (tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis. It is a serine protease inhibitor (serpin) protein (SERPINE1). PAI1 is mainly produced by the endothelium, but is also secreted by other tissue types, such as adipose tissue. PAI1 is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI1 increase with age and are elevated in conditions such as normal pregnancy and sepsis.

Storage and Stability

Store kit components at 4C. Store unopened plate and any unused microtiter strips in the pouch with desiccant. Reconstituted standards and primary antibody may be stored at -70C for later use. DO NOT freeze/thaw the standards and primary antibody more than once. All other unused kit components must be stored at 4C. Kit should be used no later than the expiration date.

Range

0-112.5 ng/mL

Sensitivity

0.181 ng/mL

Sample Types

Human plasma

Kit Content

Pre-coated 96-well plate, Anti-Human PAI1 primary antibody, HRP-conjugated secondary antibody, standards, buffers, TMB.

spezie

Human

detection target

Human Active PAI1

alias

PAI, PAI-1, PAI1, PLANH1, plasminogen activator inhibitor, type I, plasminogen activator inhibitor-1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

sensitivity

0.181 ng/mL

detection range

0-112.5 ng/mL

sample size

1

pack size

PP

UNSPSC

41116126