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CD40
and the most popular subtypes like CD40+
| CD40 Gene ID | 958 |
|---|---|
| CD40 Official Full Name | CD40 molecule |
| CD40 Alias | TNFRSF5 |
| CD40 Cellular Expression | B; Dendritic; Endothelial; Epithelial; Macrophage; monocytes |
| CD40 Ligand/Receptor/Association | CD154 |
| CD40 Function | Cell adhesion, cell proliferation, and signal transduction |
| CD40 Summary | This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014] |
All relevant products for CD40 and CD40+
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Product Code: E11C0018 -
Product Code: E11C0048
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Bovine Cluster Of Differentiation 40 Ligand (CD40L) ELISA Kit - DlDevelop
Sensitivity: 0.18ng/mLDowiedz się więcej
Detection: 0.625-40ng/mL -
Canine CD 40 Ligand ELISA
Sensitivity: 1.0pg/mLDowiedz się więcej
Detection: 50-1000pg/mLProduct Code: E08C0018 -
Product Code: E08C0048
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Canine Cluster Of Differentiation 40 Ligand (CD40L) ELISA Kit - DL-CD40L-c
Sensitivity: 0.032ng/mLDowiedz się więcej
Detection: 0.156-10ng/mL -
CD40L - 650120096
Sensitivity: < 0.17 ng / mlDowiedz się więcej
Detection: 0.31 ng / ml - 10 ng / mlProduct Code: 650120096 -
CD40L - 650120192
Sensitivity: < 0.062 ng/mlDowiedz się więcej
Detection: 0.16 ng/ml - 10 ng/mlProduct Code: 650120192 -
CD40L - 660070096
Sensitivity: < 0.062 ng/mlDowiedz się więcej
Detection: 0.16 ng/ml - 10 ng/mlProduct Code: 660070096 -
CD40L - 660070192
Sensitivity: 0.14 ng/mlDowiedz się więcej
Detection: 20 - 0.31 ng/mlProduct Code: 660070192 -
Product Code: E12C0018
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Product Code: E12C0048
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Product Code: E06C0018
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Product Code: E06C0048
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Guinea pig CD 40 Ligand ELISA
Sensitivity: 1.0pg/mLDowiedz się więcej
Detection: 50-1000pg/mLProduct Code: E05C0018
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