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CD282
and the most popular subtypes like CD282+
| CD282 Gene ID | 7097 |
|---|---|
| CD282 Official Full Name | toll like receptor 2 |
| CD282 Alias | TLR2 |
| CD282 Cellular Expression | Dendritic; Epithelial; Granulocyte; Macrophage; monocytes |
| CD282 Ligand/Receptor/Association | lipoproteins, glycans |
| CD282 Function | Mediator of innate immunity against bacterial cell wall lipoproteins. Induces activation of NFkB |
| CD282 Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
All relevant products for CD282 and CD282+
-
Human CD281 ELISA Kit - abx257473
Sensitivity: < 0.094 ng/mlDowiedz się więcej
Detection: 0.156 ng/ml - 10 ng/mlProduct Code: abx257473
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