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CD276 Gene ID | 80381 |
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CD276 Official Full Name | CD276 molecule |
CD276 Alias | B7-H3 |
CD276 Cellular Expression | T; B; NK; Dendritic; Epithelial; Macrophage; monocytes |
CD276 Ligand/Receptor/Association | |
CD276 Function | Enhances the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling |
CD276 Summary | This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008] |