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CD16a Gene ID | 14131 |
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CD16a Official Full Name | Fc receptor, IgG, low affinity III |
CD16a Alias | FcγRIIIA, FCGR3A, FCG3, FCGR3, IGFR3 |
CD16a Cellular Expression | T; NK; Dendritic; Granulocyte; Macrophage |
CD16a Ligand/Receptor/Association | aggregated IgG, IgG-Ag complex |
CD16a Function | Low affinity Fc receptor. Mediates phagocytosis and antibody-dependent T-cell-mediated cytotoxicity |
CD16a Summary | CD16 is a low affinity Fc receptor. It is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.[1] It can be used to isolate populations of these cells by antibodies directed towards CD16, using fluorescent-activated cell sorting or magnetic-activated cell sorting |
CD16b Gene ID | 2215 |
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CD16b Official Full Name | Fc fragment of IgG receptor IIIb |
CD16b Alias | FcγRIIIB, FCGR3B, FCG3, FCGR3, IGFR3 |
CD16b Cellular Expression | Granulocyte |
CD16b Ligand/Receptor/Association | IgG |
CD16b Function | Low affinity Fc receptor |
CD16b Summary | The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012] |