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CD138
and the most popular subtypes like CD138+
| CD138 Gene ID | 6382 |
|---|---|
| CD138 Official Full Name | syndecan 1 |
| CD138 Alias | Syndecan-1, SDC |
| CD138 Cellular Expression | B; Endothelial; Epithelial; Stem cell |
| CD138 Ligand/Receptor/Association | extracellular matrix, FGF |
| CD138 Function | Cell proliferation, cell migration, and cell-matrix interactions |
| CD138 Summary | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] |
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