CD130

and the most popular subtypes like CD130+

CD130 Gene ID	3572
CD130 Official Full Name	interleukin 6 signal transducer
CD130 Alias	IL-6Rβ, gp130, IL6ST
CD130 Cellular Expression	T; B; NK; Endothelial; Epithelial; Granulocyte; Macrophage; monocytes; Stem cell
CD130 Ligand/Receptor/Association
CD130 Function	Transmits activities of IL6, IL11, LIF and CNF
CD130 Summary	The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]