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CD70
and the most popular subtypes like CD70+
CD70 Gene ID
970
CD70 Official Full Name
CD70 molecule
CD70 Alias
Ki-24, CD27L, TNFSF7
CD70 Cellular Expression
T; B
CD70 Ligand/Receptor/Association
CD27
CD70 Function
Induces proliferation of costimulated T-cells. Enhances the generation of cytotoxic T-cells and contributes to T-cell activation.
CD70 Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]