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CD48 Gene ID | 962 |
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CD48 Official Full Name | CD48 molecule |
CD48 Alias | Blast-1, BCM1 |
CD48 Cellular Expression | T; B; NK; Dendritic; Macrophage; Stem cell |
CD48 Ligand/Receptor/Association | CD244 |
CD48 Function | Cell adhesion and T-cell costimulation |
CD48 Summary | This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |