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CD25 - Rabbit - Human
and the most popular subtypes like CD25+
CD25 Gene ID
3559
CD25 Official Full Name
interleukin 2 receptor subunit alpha
CD25 Alias
Tac, p55, IL2RA
CD25 Cellular Expression
T; B; NK; Dendritic; Macrophage; monocytes
CD25 Ligand/Receptor/Association
IL-2
CD25 Function
Receptor for IL2
CD25 Summary
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]