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CD124
and the most popular subtypes like CD124+
| CD124 Gene ID | 3566 |
|---|---|
| CD124 Official Full Name | interleukin 4 receptor |
| CD124 Alias | IL4RA, IL4R |
| CD124 Cellular Expression | T; B; Endothelial; Epithelial; Macrophage; monocytes; Stem cell |
| CD124 Ligand/Receptor/Association | IL-4, IL-13 |
| CD124 Function | Receptor for IL4 and IL13 |
| CD124 Summary | This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012] |
All relevant products for CD124 and CD124+
-
Human IL-4R / CD124 ELISA Kit
Sensitivity: 15.19 pg/mlLearn More
Detection: 31.25-2000 pg/mlProduct Code: KIT10402-1
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