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CD116 Gene ID | 1438 |
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CD116 Official Full Name | colony stimulating factor 2 receptor alpha subunit |
CD116 Alias | GM-CSFRα, CSF2RA, GM-CSFR |
CD116 Cellular Expression | Dendritic; Endothelial; Granulocyte; Macrophage; monocytes |
CD116 Ligand/Receptor/Association | GM-CSF |
CD116 Function | Myeloid cell hematopoiesis and differentiation |
CD116 Summary | The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008] |