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CD8
and the most common subtypes like CD8a, CD8b and CD8+
CD8a - Cluster of differentiation 8a
| CD8a Gene ID | 12525 |
|---|---|
| CD8a Official Full Name | CD8 antigen, alpha chain |
| CD8a Alias | T8, Leu-2, MAL, CD8 alpha |
| CD8a Cellular Expression | T; NK; Dendritic |
| CD8a Ligand/Receptor/Association | MHC class I |
| CD8a Function | Co-receptor for MHC class 1 molecules |
| CD8a Summary | T-cell surface glycoprotein CD8 alpha chain. Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets |
CD8b - Cluster of differentiation 8b
| CD8b Gene ID | 926 |
|---|---|
| CD8b Official Full Name | CD8b molecule |
| CD8b Alias | CD8B1, P37 |
| CD8b Cellular Expression | T |
| CD8b Ligand/Receptor/Association | MHC class I |
| CD8b Function | Co-receptor for MHC class 1 molecules |
| CD8b Summary | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010] |
All relevant products for CD8a, CD8b and CD8+
-
Human CD8 ELISA Kit
Sensitivity: < 18.75 U/mlLearn More
Detection: 31.2 U/ml - 2000 U/mlProduct Code: abx257440 -
Human CD8a ELISA Kit
Sensitivity: > 1.3 ng/mlLearn More
Detection: 3.125 ng/ml - 200 ng/mlProduct Code: abx575271 -
Human T-cell surface glycoprotein CD8 alpha chain ELISA Kit
Sensitivity: < 1.688 ng/mlLearn More
Detection: 2.81 ng/ml - 180 ng/mlProduct Code: abx250336 -
Mouse CD8 ELISA Kit
Sensitivity: 0.05pg/mlLearn More
Detection: 0.2 ng/ml -10 ng/mlProduct Code: abx157193 -
Rat T-cell surface glycoprotein CD8 alpha chain ELISA Kit
Sensitivity: < 0.094 ng/mlLearn More
Detection: 0.156 ng/ml - 10 ng/mlProduct Code: abx256377
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