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CD36
and the most popular subtypes like CD36+
| CD36 Gene ID | 948 |
|---|---|
| CD36 Official Full Name | CD36 molecule |
| CD36 Alias | GPIV, GP3B, GP4, SCARB3 |
| CD36 Cellular Expression | Dendritic; Endothelial; Erythrocyte; Macrophage; monocytes; Platelet; Stem cell |
| CD36 Ligand/Receptor/Association | oxidized LDL, thrombospondin, collagen |
| CD36 Function | Cell adhesion, cholesterol transport, scavenger receptor |
| CD36 Summary | The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014] |
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