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CD23
and the most popular subtypes like CD23+
| CD23 Gene ID | 2208 |
|---|---|
| CD23 Official Full Name | Fc fragment of IgE receptor II |
| CD23 Alias | FcεRII, BLAST-2, FCER2, CLEC4J |
| CD23 Cellular Expression | T; B; Dendritic; Epithelial; Granulocyte; Macrophage; Platelet |
| CD23 Ligand/Receptor/Association | IgE, CD21, CD11b, CD11c |
| CD23 Function | Low affinity receptor for IgE, ligand for CD19, CD21 and CD81. Key molecule for B-cell activation and growth |
| CD23 Summary | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
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