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CD37 Gene ID | 951 |
---|---|
CD37 Official Full Name | CD37 molecule |
CD37 Alias | TSPAN26,GP52-40 |
CD37 Cellular Expression | T; B; Dendritic; Granulocyte; Macrophage; monocytes |
CD37 Ligand/Receptor/Association | CD53, CD81, CD82, MHC class II |
CD37 Function | Signal transduction. Regulates T-cell proliferation |
CD37 Summary | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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