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CD314 - USA
and the most popular subtypes like CD314+
| CD314 Gene ID | 22914 |
|---|---|
| CD314 Official Full Name | killer cell lectin like receptor K1 |
| CD314 Alias | NKG2D, KLRK1 |
| CD314 Cellular Expression | T; B; NK; Granulocyte; Macrophage |
| CD314 Ligand/Receptor/Association | MICA, MICB, ULBP-1,2,3 |
| CD314 Function | Receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells |
| CD314 Summary | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
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