Rat CRP EasyTestTM ELISA kit

Brand

BioAim Scientific (Kanada)

short description

The BioAim Rat CRP EasyTestTM ELISA kit can quantitatively measure CRP in Rat serum or plasma. It is a simple and rapid technology for the quantitation of antigen in a range of sample matrices. The whole process takes less than 2.5 hours with high accuracy and precision. EasyTestTM ELISA is faster and easier to perform than standard format ELISA with less reagent handling and fewer pipetting steps.
Research Area Inflammation;

specific against

Rat

detection target

-reactive protein, pentraxin-related [(CRP)
Background: C-reactive protein (CRP) is an annular, pentameric protein found in the blood plasma, the levels of which rise in response to inflammation. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. CRP is synthesized by the liver in response to factors released by macrophages and fat cells. It is not related to C-peptide or protein C. The rat CRP gene encodes a 230 amino acid (aa) precursor with a signal peptide of 19 aa and the mature polypeptide of 211 aa. Rat CRP shares 64% and 70% aa sequence homology with human and mouse CRP respectively. Rat CRP is a glycoprotein and contains a covalently linked dimer in the pentameter.

alias

Aa1249, Ab1-341, Ab2-196, Ac1-114, Ac1262, Ac2-069, Ba2-693

sensitivity

29 pg/ml

detection range

163.8-40000 pg/ml

sample type

Serum

pack size

1x96 Wells

Assay time

2.5 h

Principle of the Elisa

Sandwich ELISA

SwissProtID

P48199