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CD354 Gene ID | 54210 |
---|---|
CD354 Official Full Name | triggering receptor expressed on myeloid cells 1 |
CD354 Alias | TREM-1 |
CD354 Cellular Expression | T; B; NK; Dendritic; Granulocyte; Macrophage; monocytes |
CD354 Ligand/Receptor/Association | |
CD354 Function | Stimulates neutrophil and monocyte-mediated inflammatory responses.Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers |
CD354 Summary | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
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