Human VEGF R3 EasyTestTM ELISA kit

Brand

BioAim Scientific (Kanada)

short description

The BioAim Human VEGF R3 EasyTestTM ELISA kit can quantitatively measure VEGF R3 in human serum or plasma. It is a simple and rapid technology for the quantitation of antigen in a range of sample matrices. The whole process takes less than 1.5 hours with high accuracy and precision. EasyTestTM ELISA is faster and easier to perform than standard format ELISA with less reagent handling and fewer pipetting steps.
Research Area wound healing; tumor growth; vascular disease;

specific against

Human

detection target

Vascular endothelial growth factor receptor 3(VEGF R3)
Background: VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

alias

AI323512, Chy, Flt-4, VEGFR-3, VEGFR3

sensitivity

15 pg/ml

detection range

65.5-16000 pg/ml

sample type

Serum

pack size

1x96 Wells

Assay time

1.5 h

Principle of the Elisa

Sandwich ELISA

SwissProtID

P35916