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Human TIM-1 ELISA Kit

Product Code: BAS-3010141

Verfügbarkeit: Auf Lager

Human TIM-1 ELISA Kit

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Beschreibung

Details

Human TIM-1 ELISA Kit

Brand

BioAim Scientific (Kanada)

short description

The Bioaim Human TIM-1 ELISA kit is a solid phase sandwich ELISA (enzyme-linked immunosorbent assay) for the quantitative measurement of TIM-1 in human serum and plasma. An antibody specific for human TIM-1 was coated on a 96-well plate. Standards and samples are added to the wells and any TIM-1 present binds to the immobilized antibody. The wells are washed and biotinylated anti-human TIM-1 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is added to the wells. The wells are again washed and TMB substrate solution is added, which produces a blue color in direct proportion to the amount of TIM-1 present in the initial sample. The Stop Solution changes the color from blue to yellow, and the microwell absorbances are read at 450 nm.
Research Area Kidney biomarker; Cardiovascular disease;

specific against

Human

detection target

hepatitis A virus cellular receptor 1 ( TIM-1 )
Background: TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 is preferentially expressed on Th2 cells and has been identified as a stimulatory molecule for T-cell activation. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus.

alias

CD365, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1

sensitivity

2 pg/ml

detection range

12.3-3000 pg/ml

sample type

Serum, plasma, Cell culture supernatant

pack size

1x96 Wells

Assay time

4.5 h

Principle of the Elisa

Sandwich ELISA

SwissProtID

Q96D42

Weitere Informationen

Weitere Informationen

Menge 1x96 Wells
Hersteller BioAim Scientific
Herstellerland Kanada
Sensitivity 2 pg/ml
Specific Against Human
Antigen Name hepatitis A virus cellular receptor 1 
Detection Range 12.3-3000 pg/ml
Alias CD365, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1
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