BioAim Scientific (Kanada)
The Bioaim Human SLAM ELISA kit is a solid phase sandwich ELISA (enzyme-linked immunosorbent assay) for the quantitative measurement of SLAM in Human serum, plasma and cell culture media. An antibody specific for Human SLAM was coated on a 96-well plate. Standards and samples are added to the wells and any SLAM present binds to the immobilized antibody. The wells are washed and biotinylated anti-Human SLAM antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is added to the wells. The wells are again washed and TMB substrate solution is added, which produces a blue color in direct proportion to the amount of SLAM present in the initial sample. The Stop Solution changes the color from blue to yellow, and the microwell absorbances are read at 450 nm.Research Area Hematologic Cancer;
signaling lymphocytic activation molecule family member 1 (SLAM) Background: SLAM, also known as CD150, is a transmembrane glycoprotein that is upregulated on activated B cells and T cells but downregulated on Th2 polarized cells. SLAM ligation promotes the activation of Th0/Th1 cells, B cells, eosinophils, mast cell, and macrophages. SLAM also functions as a cellular entry receptor for measles virus. The Signaling Lymphocytic Activation Molecule (SLAM) family of receptor molecules is a subset of the CD2 family of receptors. SLAM proteins function as co-receptors for lymphocyte activation and/or adhesion and mediate tyrosine phosphorylation signals. SLAM receptor expression is mainly restricted to immune cells. SLAMF1 belongs to the signaling lymphocytic activation molecule family.
CD150, CDw150, SLAM
Serum, plasma, Cell culture supernatant
|Antigen Name||signaling lymphocytic activation molecule family member 1|
|Detection Range||61.4-15000 pg/ml|
|Alias||CD150, CDw150, SLAM|