BioAim Scientific (Kanada)
The Bioaim Human LYVE-1 ELISA kit is a solid phase sandwich ELISA (enzyme-linked immunosorbent assay) for the quantitative measurement of LYVE-1 in Human serum, plasma and cell culture media. An antibody specific for Human LYVE-1 was coated on a 96-well plate. Standards and samples are added to the wells and any LYVE-1 present binds to the immobilized antibody. The wells are washed and biotinylated anti-Human LYVE-1 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is added to the wells. The wells are again washed and TMB substrate solution is added, which produces a blue color in direct proportion to the amount of LYVE-1 present in the initial sample. The Stop Solution changes the color from blue to yellow, and the microwell absorbances are read at 450 nm.Research Area Angiogenesis; cell adhesion;
lymphatic vessel endothelial hyaluronan receptor 1(LYVE-1) Background: Lymphatic Vessel Endothelial Hyaluronan (HA) Receptor-1 (LYVE-1) is a 60-kDa type I transmembrane glycoprotein. LYVE-1 is expressed on both the lumenal and ablumenal surfaces of lymphatic endothelium, and also on hepatic blood sinusoidal endothelia. This expression pattern, combined with studies showing that LYVE-1 can support cellular HA internalization in vitro, may suggest LYVE-1 participation in HA internalization for degradation, or transport of HA from tissues into the lumen of lymphatic vessels.
CRSBP-1, HAR,LYVE-1, XLKD1
Serum, plasma, Cell culture supernatant
|Antigen Name||lymphatic vessel endothelial hyaluronan receptor 1|
|Detection Range||8.2-2000 pg/ml|
|Alias||CRSBP-1, HAR,LYVE-1, XLKD1|