×

Registrierung

Profile Informationen

Login Daten

oder Einloggen

Vorname ist erforderlich!
Nachname ist erforderlich!
Vorname ist ungültig!
Nachname ist ungültig!
Dies ist keine E-Mail-Adresse!
E-Mail-Adresse ist erforderlich!
Dies E-Mail-Adresse ist bereit registriert!
Passwort ist erforderlich!
Geben Sie ein gültiges Passwort ein!
Bitte geben Sie 6 oder mehr Zeichen ein!
Bitte geben Sie 16 oder weniger Zeichen ein!
Passwörter sind nicht dasselbe!
Geschäftsbedingungen sind erforderlich!
E-Mail oder Passwort ist falsch!

Human IL-6 EasyTestTM ELISA kit

Product Code: BAS-1010018

Verfügbarkeit: Auf Lager

Human IL-6 EasyTestTM ELISA kit

Bewerten Sie dieses Produkt als Erster

OR

Fragen zur Lieferzeit

Angebot anfordern

Beschreibung

Details

Human IL-6 EasyTestTM ELISA kit

Brand

BioAim Scientific (Kanada)

short description

The BioAim Human IL-6 EasyTestTM ELISA kit can quantitatively measure IL-6 in human serum or plasma. It is a simple and rapid technology for the quantitation of antigen in a range of sample matrices. The whole process takes less than 1.5 hours with high accuracy and precision. EasyTestTM ELISA is faster and easier to perform than standard format ELISA with less reagent handling and fewer pipetting steps.
Research Area Cancer Biomarker; inflammation;

specific against

Human

detection target

interleukin 6(IL-6)
Background: IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha. Recent work has shown that both upstream and downstream signalling pathways for IL-6 differ markedly between myocytes and macrophages. It appears that unlike IL-6 signalling in macrophages, which is dependent upon activation of the NFκB signalling pathway, intramuscular IL-6 expression is regulated by a network of signalling cascades, including the Ca2+/NFAT and glycogen/p38 MAPK pathways. Thus, when IL-6 is signalling in monocytes or macrophages, it creates a pro-inflammatory response, whereas IL-6 activation and signalling in muscle is totally independent of a preceding TNF-response or NFκB activation, and is anti-inflammatory.

alias

CDF, HSF, BSF-2, IL-6, IFNB2, HGF, BSF2, IFN-beta-2

sensitivity

< 1 pg/ml

detection range

20.5-5000 pg/ml

sample type

Serum

pack size

1x96 Wells

Assay time

1.5 h

Principle of the Elisa

Sandwich ELISA

SwissProtID

P05231

Weitere Informationen

Weitere Informationen

Menge 1x96 Wells
Hersteller BioAim Scientific
Herstellerland Kanada
Sensitivity < 1 pg/ml
Specific Against Human
Antigen Name interleukin 6
Detection Range 20.5-5000 pg/ml
Alias CDF, HSF, BSF-2, IL-6, IFNB2, HGF, BSF2, IFN-beta-2
Bewertungen
Tags

Produkttags

Verwenden Sie Leerzeichen um Tags zu trennen. Verwenden Sie Apostrophe (') für Phrasen.

Datasheet

Video