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Human DLL1 ELISA Kit

Product Code: BAS-3010178

Verfügbarkeit: Auf Lager

Human DLL1 ELISA Kit

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Beschreibung

Details

Human DLL1 ELISA Kit

Brand

BioAim Scientific (Kanada)

short description

The Bioaim Human DLL1 ELISA kit is a solid phase sandwich ELISA (enzyme-linked immunosorbent assay) for the quantitative measurement of DLL1 in Human serum, plasma and cell culture media. An antibody specific for Human DLL1 was coated on a 96-well plate. Standards and samples are added to the wells and any DLL1 present binds to the immobilized antibody. The wells are washed and biotinylated anti-Human DLL1 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is added to the wells. The wells are again washed and TMB substrate solution is added, which produces a blue color in direct proportion to the amount of DLL1 present in the initial sample. The Stop Solution changes the color from blue to yellow, and the microwell absorbances are read at 450 nm.
Research Area angiogenesis, cell survival, and the immune response;

specific against

Human

detection target

delta like canonical Notch ligand 1 (DLL1)
Background: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in central nervous system morphogenesis, intervertebral joint formation, inner ear hair cell development and patterning, and arteriogenesis. It regulates the homeostasis and differentiation of neural, pancreatic, and myogenic progenitor cells, T and B lymphocytes. DLL1 is overexpressed in a number of cancers and contributes to tumorigenesis. The extracellular region of DLL1 can be shed from the cell surface, and the intracellular domain can be cleaved by gamma-secretase to translocate to the nucleus and regulate gene transcription. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.

alias

DELTA1, DL1, Delta

sensitivity

25 pg/ml

detection range

49.2-12000 pg/ml

sample type

Serum, plasma, Cell culture supernatant

pack size

1x96 Wells

Assay time

4.5 h

Principle of the Elisa

Sandwich ELISA

SwissProtID

O00548

Weitere Informationen

Weitere Informationen

Menge 1x96 Wells
Hersteller BioAim Scientific
Herstellerland Kanada
Sensitivity 25 pg/ml
Specific Against Human
Antigen Name delta like canonical Notch ligand 1 
Detection Range 49.2-12000 pg/ml
Alias DELTA1, DL1, Delta
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