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Human C1q R1 ELISA Kit

Product Code: BAS-3010160

Verfügbarkeit: Auf Lager

Human C1q R1 ELISA Kit

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Beschreibung

Details

Human C1q R1 ELISA Kit

Brand

BioAim Scientific (Kanada)

short description

The Bioaim Human C1q R1 ELISA kit is a solid phase sandwich ELISA (enzyme-linked immunosorbent assay) for the quantitative measurement of C1q R1 in Human serum, plasma and cell culture media. An antibody specific for Human C1q R1 was coated on a 96-well plate. Standards and samples are added to the wells and any C1q R1 present binds to the immobilized antibody. The wells are washed and biotinylated anti-Human C1q R1 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is added to the wells. The wells are again washed and TMB substrate solution is added, which produces a blue color in direct proportion to the amount of C1q R1 present in the initial sample. The Stop Solution changes the color from blue to yellow, and the microwell absorbances are read at 450 nm.
Research Area Immune response;

specific against

Human

detection target

CD93 molecule(C1q R1)
Background: C1q R1 is also known as C1q Rp, collectin receptor, and AA4 antigen. C1q R1 mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL, and SP-A. It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets, and cells of myeloid origin.  CD93 was initially thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein contains two highly conserved domains which may be involved in CD93 function.

alias

C1QR1, C1qR(P), C1qRP, CDw93, ECSM3, MXRA4, dJ737E23.1

sensitivity

15 pg/ml

detection range

24.6-6000 pg/ml

sample type

Serum, plasma, Cell culture supernatant

pack size

1x96 Wells

Assay time

4.5 h

Principle of the Elisa

Sandwich ELISA

SwissProtID

Q9NPY3

Weitere Informationen

Weitere Informationen

Menge 1x96 Wells
Hersteller BioAim Scientific
Herstellerland Kanada
Sensitivity 15 pg/ml
Specific Against Human
Antigen Name CD93 molecule
Detection Range 24.6-6000 pg/ml
Alias C1QR1, C1qR(P), C1qRP, CDw93, ECSM3, MXRA4, dJ737E23.1
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