Human BDNF EasyTestTM ELISA kit

Brand

BioAim Scientific (Kanada)

short description

The BioAim Human BDNF EasyTest™ ELISA  kit can quantitatively measure human BDNF in serum and plasma. It is a simple and rapid technology for the quantitation of antigen in a range of sample matrices. The whole process takes only 1.5 hours with high accuracy and precision. EasyTestTM ELISA is faster and easier to perform than standard format ELISA with less reagent handling and fewer pipetting steps.
Research Area Neural differentiation and survival;

specific against

Human

detection target

brain-derived neurotrophic factor(BDNF)
Background: BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.

alias

BULN2, ANON2

sensitivity

1 pg/ml

detection range

93.8-6000 pg/ml

sample type

Serum

pack size

1x96 Wells

Assay time

1.5 h

Principle of the Elisa

Sandwich ELISA

SwissProtID

P23560