Product Description:Guanine nucleotide exchange factors (GEFs) activate the small GTPases by catalyzing the exchange of GDP for GTP. Our Active Rac-GEF Assay Kit employs the visible agarose bead technology used in our Small GTPase Activation Assays to pull down the active form of Rac-GEF from endogenous lysates or purified samples. The specific GEF known as Tiam1 is then specifically detected with a polyclonal antibody.
Product Line:Cell Signaling and Protein Biology
Product Classification:Cell Signaling and Protein Biology->G Protein Signaling / Small GTPase Assays and Vectors->Small GTPase Research Tools ->Small GTPase Active GEF Assays
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